Masteron Propionate
Masteron Propionate
Drostanolone Propionate provides a hard, dry look. Anti-estrogenic properties make it excellent for contest prep and cutting.
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- Refund + retest if a batch fails purity
Complete protocols
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Stacks that include Masteron Propionate — protocol components priced together, bulk savings applied automatically.
At a glance
At a glance
- Concentration
- 100mg/ml
- Purity
- USP-equivalent ≥98%
- Route
- Intramuscular injection
- Storage
- Room temperature, protect from light.
Compound profile
Masteron Propionate is the trade name for Drostanolone Propionate, a dihydrotestosterone (DHT) derivative with a 2-alpha methyl group that protects it from metabolic breakdown by 3-hydroxysteroid dehydrogenase in muscle tissue. Drostanolone was originally developed as a pharmaceutical treatment for breast cancer due to its potent anti-estrogenic properties — it acts as a competitive inhibitor at the estrogen receptor and may also inhibit aromatase enzyme activity. With an anabolic rating of 62-130 and an androgenic rating of 25-40, Masteron is classified as a moderate anabolic with pronounced cosmetic and anti-estrogenic effects.
Masteron Propionate is the trade name for Drostanolone Propionate, a dihydrotestosterone (DHT) derivative with a 2-alpha methyl group that protects it from metabolic breakdown by 3-hydroxysteroid dehydrogenase in muscle tissue. Drostanolone was originally developed as a pharmaceutical treatment for breast cancer due to its potent anti-estrogenic properties — it acts as a competitive inhibitor at the estrogen receptor and may also inhibit aromatase enzyme activity. With an anabolic rating of 62-130 and an androgenic rating of 25-40, Masteron is classified as a moderate anabolic with pronounced cosmetic and anti-estrogenic effects.
As a DHT derivative, Drostanolone cannot aromatize to estrogen under any circumstances — there is no substrate for the aromatase enzyme to act upon. Its anti-estrogenic mechanism is twofold: direct competition at estrogen receptors in breast and other tissues, and modest inhibition of aromatase enzyme activity that reduces conversion of other aromatizable compounds in a stack. In muscle tissue, Masteron promotes a hard, dry, grainy appearance by reducing subcutaneous water retention and enhancing the visual separation between muscle groups. It also binds SHBG (sex hormone-binding globulin) with high affinity, freeing a greater fraction of co-administered testosterone to exist in its bioactive unbound state.
Masteron Propionate is the pre-contest and cutting-phase specialist. Its value is not in raw mass accrual — milligram for milligram, it adds less tissue than testosterone, nandrolone, or trenbolone — but in the quality and appearance of the physique it produces. Researchers report a pronounced hardening and drying effect that becomes visible within the first 7-10 days of administration, with progressive improvement throughout the cycle. The anti-estrogenic support it provides can reduce or eliminate the need for pharmaceutical aromatase inhibitors when stacked with moderate-dose testosterone.
This compound is best suited for researchers who are already at a relatively low body fat percentage (sub-15%) where its cosmetic effects can be appreciated. On a researcher carrying significant subcutaneous fat, Masteron's hardening and drying effects will be largely invisible. It is appropriate for intermediate to advanced researchers running cutting, recomposition, or pre-competition protocols. It also serves as a functional AI alternative in stacks where researchers wish to avoid the lipid impact of pharmaceutical aromatase inhibitors.
Masteron Propionate has a half-life of approximately 2-3 days, requiring injection every other day or three times weekly. Standard research doses range from 300-500mg/week. It pairs exceptionally well with Testosterone Propionate (for ester-matched cutting stacks), Trenbolone Acetate (for advanced cutting and contest preparation), and Winstrol (for maximum drying and hardening). PCT protocols follow standard timelines for short-ester compounds, with SERM therapy commencing 3-5 days after the final injection.
How to use
Injection technique, site rotation, and frequency guidance. Typical protocols split the weekly dose into 2 injections.
Dose ranges published in the peptide-research literature vary considerably. Research protocols should be designed by a qualified researcher and use the lowest effective dose consistent with the hypothesis being tested. Half-life determines dosing frequency — shorter half-lives usually require daily dosing, while long-acting analogues tolerate weekly administration.
For compound-specific dose theory, see the half-life dosing math guide and the stacking theory reference.
Independent lab verification
Research disclaimer
For research and laboratory use only. Not for human or veterinary consumption. Nova Pharma sells to qualified researchers of legal age and ships to Canadian addresses only. See disclaimer and terms.
At a glance
At a glance
- Concentration
- 100mg/ml
- Purity
- USP-equivalent ≥98%
- Route
- Intramuscular injection
- Storage
- Room temperature, protect from light.
Compound profile
Masteron Propionate is the trade name for Drostanolone Propionate, a dihydrotestosterone (DHT) derivative with a 2-alpha methyl group that protects it from metabolic breakdown by 3-hydroxysteroid dehydrogenase in muscle tissue. Drostanolone was originally developed as a pharmaceutical treatment for breast cancer due to its potent anti-estrogenic properties — it acts as a competitive inhibitor at the estrogen receptor and may also inhibit aromatase enzyme activity. With an anabolic rating of 62-130 and an androgenic rating of 25-40, Masteron is classified as a moderate anabolic with pronounced cosmetic and anti-estrogenic effects.
Masteron Propionate is the trade name for Drostanolone Propionate, a dihydrotestosterone (DHT) derivative with a 2-alpha methyl group that protects it from metabolic breakdown by 3-hydroxysteroid dehydrogenase in muscle tissue. Drostanolone was originally developed as a pharmaceutical treatment for breast cancer due to its potent anti-estrogenic properties — it acts as a competitive inhibitor at the estrogen receptor and may also inhibit aromatase enzyme activity. With an anabolic rating of 62-130 and an androgenic rating of 25-40, Masteron is classified as a moderate anabolic with pronounced cosmetic and anti-estrogenic effects.
As a DHT derivative, Drostanolone cannot aromatize to estrogen under any circumstances — there is no substrate for the aromatase enzyme to act upon. Its anti-estrogenic mechanism is twofold: direct competition at estrogen receptors in breast and other tissues, and modest inhibition of aromatase enzyme activity that reduces conversion of other aromatizable compounds in a stack. In muscle tissue, Masteron promotes a hard, dry, grainy appearance by reducing subcutaneous water retention and enhancing the visual separation between muscle groups. It also binds SHBG (sex hormone-binding globulin) with high affinity, freeing a greater fraction of co-administered testosterone to exist in its bioactive unbound state.
Masteron Propionate is the pre-contest and cutting-phase specialist. Its value is not in raw mass accrual — milligram for milligram, it adds less tissue than testosterone, nandrolone, or trenbolone — but in the quality and appearance of the physique it produces. Researchers report a pronounced hardening and drying effect that becomes visible within the first 7-10 days of administration, with progressive improvement throughout the cycle. The anti-estrogenic support it provides can reduce or eliminate the need for pharmaceutical aromatase inhibitors when stacked with moderate-dose testosterone.
This compound is best suited for researchers who are already at a relatively low body fat percentage (sub-15%) where its cosmetic effects can be appreciated. On a researcher carrying significant subcutaneous fat, Masteron's hardening and drying effects will be largely invisible. It is appropriate for intermediate to advanced researchers running cutting, recomposition, or pre-competition protocols. It also serves as a functional AI alternative in stacks where researchers wish to avoid the lipid impact of pharmaceutical aromatase inhibitors.
Masteron Propionate has a half-life of approximately 2-3 days, requiring injection every other day or three times weekly. Standard research doses range from 300-500mg/week. It pairs exceptionally well with Testosterone Propionate (for ester-matched cutting stacks), Trenbolone Acetate (for advanced cutting and contest preparation), and Winstrol (for maximum drying and hardening). PCT protocols follow standard timelines for short-ester compounds, with SERM therapy commencing 3-5 days after the final injection.
How to use
Injection technique, site rotation, and frequency guidance. Typical protocols split the weekly dose into 2 injections.
Dose ranges published in the peptide-research literature vary considerably. Research protocols should be designed by a qualified researcher and use the lowest effective dose consistent with the hypothesis being tested. Half-life determines dosing frequency — shorter half-lives usually require daily dosing, while long-acting analogues tolerate weekly administration.
For compound-specific dose theory, see the half-life dosing math guide and the stacking theory reference.
Independent lab verification
Research disclaimer
For research and laboratory use only. Not for human or veterinary consumption. Nova Pharma sells to qualified researchers of legal age and ships to Canadian addresses only. See disclaimer and terms.
Read the research
Reference articles from the lab covering this compound.
best of
Best Steroids for Cutting 2026: Compounds That Get You Stage-Ready
The definitive 2026 ranking of the best steroids for cutting — from Trenbolone to Primobolan. Complete cutting stacks for beginner, intermediate, and advanced users with protocols and timelines.
comparisons
Masteron Propionate vs Enanthate: Choosing the Right Ester for Your Cut
Masteron Propionate vs Enanthate — compare half-lives, injection frequency, onset speed, cost, peak week control, and dosing equivalence. Learn when to choose each drostanolone ester for cutting cycles and contest prep.
compound guides
Masteron for Contest Prep: The Hardening Agent Every Competitor Uses
Masteron (drostanolone) for contest prep — how the DHT-derivative creates the dry, grainy look on stage. Dosing protocols, body fat thresholds, stacking with Tren and Test, Prop vs Enanthate ester choice, and hair loss risk.
